SCHEMBL8809641

SCHEMBL8809641

COc1nncc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
CYP1A2 P05177 3/20 0.59
CYP2C19 P33261 1/20 0.59
NPC1 O15118 6/20 0.56
RAB9A P51151 6/20 0.56
TP53 P04637 5/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
LMNA P02545 5/20 0.56
KDM4E B2RXH2 2/20 0.56
CYP3A4 P08684 2/20 0.56
GOT1 P17174 2/20 0.56
PKM P14618 2/20 0.56
CYP2D6 P10635 2/20 0.56
MPO P05164 1/20 0.56
MAOA P21397 1/20 0.56
PTGS1 P23219 1/20 0.56
THPO P40225 1/20 0.56
AOX1 Q06278 1/20 0.56
ACOX1 Q15067 1/20 0.56
MAPT P10636 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29674926 1.00 ALDH1A1 (0.59) ALDH1A1CYP1A2CYP2C19NPC1RAB9A
SCHEMBL9461493 0.83 LMNA (0.56) ALDH1A1CYP1A2NPC1RAB9ATP53
SCHEMBL599375 0.82 LMNA (0.51) ALDH1A1CYP1A2NPC1RAB9ATP53
SCHEMBL8808680 0.79 LMNA (0.52) ALDH1A1CYP1A2NPC1RAB9ATP53
SCHEMBL21965729 0.79 LMNA (0.43) ALDH1A1CYP1A2NPC1RAB9ATP53
Formaldehyde SCHEMBL23529395 0.78 LMNA (0.52) ALDH1A1CYP1A2NPC1RAB9ATP53
Hydrochloric Acid SCHEMBL2488955 0.78 LMNA (0.51) ALDH1A1CYP1A2NPC1RAB9ATP53
Sulfur Dioxide SCHEMBL27498686 0.77 LMNA (0.51) ALDH1A1CYP1A2NPC1RAB9ATP53
SCHEMBL8809522 0.77 RAB9A (0.58) ALDH1A1CYP1A2NPC1RAB9ATP53
SCHEMBL7630666 0.77 LMNA (0.50) ALDH1A1CYP1A2NPC1RAB9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12429483-B2 System and method for determining onset and disease progression RESPIRATION SCAN LTD (IL) 2025-09-30 US claimed
EP-0539805-B1 Phthalazines substituted on position 1 by an ether group and process for their preparation ASTA MEDICA AG (DE) 1997-09-03 EP claimed
US-5354750-A Analgesics, antinflammatory, anticonvulsive and antipyretic agents ASTA MEDICA AKTIENGESELLSCHAFT (DE) 1994-10-11 US claimed
EP-0539805-A1 Phthalazines substituted on position 1 by an ether or a thioether group and process for their preparation ASTA Medica Aktiengesellschaft (DE) 1993-05-05 EP claimed
JP-5222002-A None JP disclosed
US-12429483-B2 System and method for determining onset and disease progression RESPIRATION SCAN LTD (IL) 2025-09-30 US disclosed
EP-4164481-B1 A DEVICE FOR MEASURING VOLATILE MARKERS IN BREATH NANOSE MEDICAL LTD (IL) 2024-10-16 EP disclosed
US-20230337934-A1 A DEVICE FOR MEASURING VOLATILE MARKERS IN BREATH NANOSE MEDICAL LTD (IL) 2023-10-26 US disclosed
EP-4164481-A1 A DEVICE FOR MEASURING VOLATILE MARKERS IN BREATH Nanose Medical Ltd (IL) 2023-04-19 EP disclosed
US-20220317122-A1 SYSTEM AND METHOD FOR DETERMINING ONSET AND DISEASE PROGRESSION RESPIRATION SCAN LTD. (IL) 2022-10-06 US disclosed
EP-4013302-A1 SYSTEM AND METHOD FOR DETERMINING ONSET AND DISEASE PROGRESSION Respiration Scan Ltd (IL) 2022-06-22 EP disclosed
WO-2021250674-A1 A DEVICE FOR MEASURING VOLATILE MARKERS IN BREATH NANOSE MEDICAL LTD (IL) 2021-12-16 WO disclosed
WO-2011115603-A1 ANTI-CORROSION AGENTS FOR TRANSPARENT CONDUCTIVE FILM CARESTREAM HEALTH, INC. (US) 2011-09-22 WO disclosed
US-20110065704-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-03-17 US disclosed
US-20110065704-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-03-17 US disclosed
WO-2010151797-A2 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR UNIVERSITY OF MASSACHUSETTS (US) 2010-12-29 WO disclosed
EP-0539805-B1 Phthalazines substituted on position 1 by an ether group and process for their preparation ASTA MEDICA AG (DE) 1997-09-03 EP disclosed
US-5354750-A Analgesics, antinflammatory, anticonvulsive and antipyretic agents ASTA MEDICA AKTIENGESELLSCHAFT (DE) 1994-10-11 US disclosed
JP-H05222002-A PHTHALAZINE CONTAINING ETHER OR THIOETHER GROUP IN 1-POSITION, ITS PREPARATION AND PHARMACEUTICAL CONTAINING THE SAME, WHICH HAS ANALGESIC, ANTI-INFLAMMATORY, ANTICONVULSIVE AND ANTI-PYRETIC ACTION, AND THEIR PREPARATION ASTA MEDICA AG 1993-08-31 JP disclosed
EP-0539805-A1 Phthalazines substituted on position 1 by an ether or a thioether group and process for their preparation ASTA Medica Aktiengesellschaft (DE) 1993-05-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110065704-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR TIA1, ZFP3, RBM3 ALDH1A1 3135/4885CYP1A2 4801/4885CYP2C19 4876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.