Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | FABP6 | P51161 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808736 | 0.77 | HRH3 (0.59) | HRH3KMT2AMEN1RAB9AOPRM1 | |
| SCHEMBL8809487 | 0.73 | HRH3 (0.86) | HRH3KMT2AMEN1RAB9AOPRM1 | |
| SCHEMBL24093171 | 0.73 | HRH3 (0.86) | HRH3KMT2AMEN1RAB9AOPRM1 | |
| SCHEMBL8809141 | 0.73 | PARP1 (0.43) | HRH3KMT2AMEN1RAB9ACD274 | |
| SCHEMBL16249332 | 0.72 | MEN1 (0.83) | HRH3KMT2AMEN1RAB9AOPRM1 | |
| SCHEMBL8809433 | 0.71 | NR1H2 (0.36) | KMT2AMEN1RAB9APOLBLMNA | |
| SCHEMBL8808822 | 0.71 | HRH3 (0.64) | HRH3KMT2AMEN1RAB9APOLB | |
| SCHEMBL8810061 | 0.70 | HRH3 (0.59) | HRH3KMT2AMEN1RAB9APOLB | |
| SCHEMBL10789534 | 0.70 | HRH3 (0.71) | HRH3KMT2AMEN1RAB9APOLB | |
| SCHEMBL294763 | 0.70 | HRH3 (0.71) | HRH3KMT2AMEN1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |