Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.71 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | FABP6 | P51161 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1847296 | 1.00 | HRH3 (0.71) | HRH3GRIN2BPOLBMEN1RAB9A | |
| SCHEMBL24574127 | 1.00 | HRH3 (0.71) | HRH3GRIN2BPOLBMEN1RAB9A | |
| SCHEMBL294763 | 1.00 | HRH3 (0.71) | HRH3GRIN2BPOLBMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL11782513 | 0.98 | HRH3 (0.69) | HRH3GRIN2BPOLBMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL11781778 | 0.98 | HRH3 (0.69) | HRH3GRIN2BPOLBMEN1RAB9A | |
| SCHEMBL433970 | 0.98 | GRIN2B (0.69) | HRH3GRIN2BPOLBMEN1RAB9A | |
| Bromide SCHEMBL18131548 | 0.96 | HRH3 (0.67) | HRH3GRIN2BPOLBMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL11785266 | 0.96 | GRIN2B (0.67) | HRH3GRIN2BPOLBMEN1RAB9A | |
| Methyl Alcohol SCHEMBL2137682 | 0.94 | HRH3 (0.65) | HRH3GRIN2BPOLBMEN1RAB9A | |
| SCHEMBL4173336 | 0.94 | GRIN2B (0.69) | HRH3GRIN2BPOLBMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124150-B1 | BENZOBICYCLONONANE AMINO DERIVATIVES WITH ANTICONVULSIVE PROPERTIES | AKZO N.V. (NL) | 1987-11-11 | — | — | EP | disclosed |
| EP-0124150-A1 | Benzobicyclononane amino derivatives with anticonvulsive properties | AKZO N.V. (NL) | 1984-11-07 | — | — | EP | disclosed |