Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810439 | 0.82 | BCHE (0.39) | PARP1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8809953 | 0.80 | PARP1 (0.53) | PARP1ALDH1A1KCNH2POLBMAP4K4 | |
| SCHEMBL8812099 | 0.77 | SMN1; SMN2 (0.39) | ALDH1A1POLBMEN1KMT2AKDM4E | |
| SCHEMBL8807848 | 0.75 | HRH3 (0.62) | PARP1ALDH1A1KCNH2POLBMAP4K4 | |
| SCHEMBL8811233 | 0.73 | KCNH2 (0.56) | PARP1ALDH1A1KCNH2POLBMAP4K4 | |
| SCHEMBL8808913 | 0.73 | HRH3 (0.50) | PARP1POLBHRH3CXCR4MEN1 | |
| SCHEMBL8809463 | 0.72 | ALDH1A1 (0.51) | PARP1ALDH1A1KCNH2POLBMAP4K4 | |
| SCHEMBL8809605 | 0.72 | ALDH1A1 (0.51) | PARP1ALDH1A1KCNH2POLBMAP4K4 | |
| SCHEMBL8809501 | 0.70 | ALDH1A1 (0.52) | PARP1ALDH1A1KCNH2POLBMAP4K4 | |
| SCHEMBL8809135 | 0.69 | MAP4K4 (0.45) | PARP1ALDH1A1KCNH2POLBMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |