Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809167 | 0.89 | PARP1 (0.62) | PARP1MAPTALDH1A1LMNANPSR1 | |
| SCHEMBL8685371 | 0.89 | PARP1 (0.62) | PARP1MAPTALDH1A1LMNANPSR1 | |
| SCHEMBL8685967 | 0.88 | PARP1 (0.50) | PARP1MAPTALDH1A1LMNANPSR1 | |
| SCHEMBL8813674 | 0.88 | TDP1 (0.48) | PARP1ALDH1A1LMNASLC2A1MEN1 | |
| SCHEMBL8809776 | 0.88 | PARP1 (0.64) | PARP1MAPTALDH1A1LMNANPSR1 | |
| SCHEMBL8809369 | 0.87 | SLC2A1 (0.46) | PARP1MAPTLMNASLC2A1MEN1 | |
| SCHEMBL8811097 | 0.85 | PARP1 (0.58) | PARP1HTR6APPSNCAPIM1 | |
| SCHEMBL8811389 | 0.85 | PARP1 (0.62) | PARP1MAPTALDH1A1LMNATP53 | |
| SCHEMBL8810613 | 0.85 | PARP1 (0.44) | PARP1HTR6APPSNCA | |
| SCHEMBL8810400 | 0.85 | PARP1 (0.46) | PARP1MAPTALDH1A1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |