Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809497 | 0.73 | RAB9A (0.61) | NPC1RAB9AS1PR1S1PR3ALDH1A1 | |
| SCHEMBL11465189 | 0.73 | NPC1 (0.42) | NPC1RAB9AS1PR1S1PR3ALDH1A1 | |
| SCHEMBL19227318 | 0.71 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL20733138 | 0.71 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL20733110 | 0.71 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL19227252 | 0.71 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL182620 | 0.71 | ALDH1A1 (0.50) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL11693073 | 0.69 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| Methyl Alcohol SCHEMBL9678518 | 0.68 | KDM4E (0.47) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| Methylamine SCHEMBL28000435 | 0.68 | KDM4E (0.47) | NPC1RAB9AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |