Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.56 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809239 | 0.73 | NPC1 (0.46) | RAB9ANPC1S1PR1S1PR3ALDH1A1 | |
| SCHEMBL28663908 | 0.71 | RAB9A (0.53) | RAB9ANPC1S1PR1S1PR3ALDH1A1 | |
| SCHEMBL9057588 | 0.68 | NPC1 (0.41) | RAB9ANPC1S1PR1S1PR3ALDH1A1 | |
| SCHEMBL14139451 | 0.67 | LCK (0.58) | NPC1ALDH1A1SMN1; SMN2L3MBTL1JAK3 | |
| SCHEMBL19227318 | 0.67 | ALDH1A1 (0.50) | RAB9ANPC1ALDH1A1SMN1; SMN2JAK3 | |
| SCHEMBL20733138 | 0.67 | ALDH1A1 (0.50) | RAB9ANPC1ALDH1A1SMN1; SMN2JAK3 | |
| SCHEMBL19227252 | 0.67 | ALDH1A1 (0.50) | RAB9ANPC1ALDH1A1SMN1; SMN2JAK3 | |
| SCHEMBL20733110 | 0.67 | ALDH1A1 (0.50) | RAB9ANPC1ALDH1A1SMN1; SMN2JAK3 | |
| SCHEMBL182620 | 0.67 | ALDH1A1 (0.50) | RAB9ANPC1ALDH1A1SMN1; SMN2JAK3 | |
| SCHEMBL20031353 | 0.66 | NOTUM (0.62) | RAB9ANPC1USP30SLC6A9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |