Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806923 | 0.75 | ALOX5 (0.73) | ALOX5 | |
| SCHEMBL9831016 | 0.74 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL8808148 | 0.72 | ALOX5 (0.68) | ALOX5 | |
| SCHEMBL8805809 | 0.71 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL8807135 | 0.71 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL8806895 | 0.70 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL8807791 | 0.67 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL8807425 | 0.67 | ALOX5 (0.60) | ALOX5 | |
| SCHEMBL8815217 | 0.66 | ALOX5 (0.55) | ALOX5 | |
| Ammonia Solution, Strong SCHEMBL8807165 | 0.66 | ALOX5 (0.97) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320628-B1 | Substituted furan compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase | ABBOTT LAB (US) | 1997-01-15 | — | — | EP | disclosed |
| US-5112848-A | Antiasthmatics and antiarthritic agents | ABBOTT LABORATORIES (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0320628-A1 | Substituted furan compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase | ABBOTT LABORATORIES (US) | 1989-06-21 | — | — | EP | disclosed |