Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.38 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834151 | 0.77 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL8809341 | 0.74 | ALOX5 (0.55) | ALOX5 | |
| SCHEMBL9833184 | 0.74 | ALOX5 (0.51) | ALOX5HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9834288 | 0.73 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL9832067 | 0.72 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL9833394 | 0.71 | ALOX5 (0.74) | ALOX5 | |
| SCHEMBL9373618 | 0.68 | ALOX5 (0.57) | ALOX5HDAC1 | |
| SCHEMBL8814587 | 0.68 | ALOX5 (0.59) | ALOX5 | |
| SCHEMBL9831384 | 0.68 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL9832426 | 0.68 | ALOX5 (0.71) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388429-A4 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | — | 1991-08-21 | — | — | EP | disclosed |
| EP-0388429-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-09-26 | — | — | EP | disclosed |
| WO-1989004299-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1989-05-18 | — | — | WO | disclosed |