Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.46 |
| ▸ | MPC2 | O95563 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8813904 | 0.93 | CA2 (0.66) | CA2PPARGFFAR1MPC2CYP2C8 | |
| SCHEMBL8811842 | 0.89 | CA2 (0.48) | CA2PPARGFFAR1MPC2CYP2C8 | |
| SCHEMBL8809709 | 0.87 | CA2 (0.51) | CA2PPARGFFAR1MPC2CYP2C8 | |
| SCHEMBL8810910 | 0.87 | PPARG (0.52) | CA2PPARGFFAR1MPC2CYP2C8 | |
| SCHEMBL8808817 | 0.86 | PTPN1 (0.51) | CA2PPARGFFAR1MPC2CYP2C8 | |
| SCHEMBL8809640 | 0.86 | CA2 (0.49) | CA2PPARGFFAR1MPC2CYP2C8 | |
| SCHEMBL8809469 | 0.81 | EGFR (0.39) | CA2KDM4EALDH1A1EGFRMAPT | |
| SCHEMBL8188658 | 0.81 | CA2 (0.81) | CA2PPARGFFAR1MPC2CYP2C8 | |
| SCHEMBL8808808 | 0.80 | PPARG (0.39) | CA2PPARGFFAR1ALDH1A1MAPT | |
| SCHEMBL8809686 | 0.79 | HTR6 (0.45) | PPARGFFAR1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |