Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 4/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809393 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL18930268 | 0.78 | LMNA (0.44) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL10875641 | 0.75 | CYP3A4 (0.39) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL1642724 | 0.75 | CYP3A4 (0.41) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL5013167 | 0.74 | CYP3A4 (0.53) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL7372312 | 0.74 | KMT2A (0.47) | ALDH1A1HTTMAPTGAAGFER | |
| SCHEMBL15314356 | 0.73 | SLC7A5 (0.51) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL31011021 | 0.72 | TDP1 (0.45) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL831043 | 0.72 | TDP1 (0.45) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL31011020 | 0.72 | TDP1 (0.45) | ALDH1A1KDM4EMAPTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502278-B1 | Polycyclic dyes | ZENECA LTD (GB) | 1997-03-05 | — | — | EP | disclosed |
| US-5374724-A | Process for the preparation of substituted acetic acids | ZENECA, LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| US-5189181-A | Process for preparation 2,6-dihydrobenzo[1:26, 4:5-6]-difuran dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-23 | — | — | US | disclosed |
| EP-0502278-A1 | Polycyclic dyes | ZENECA LIMITED (GB) | 1992-09-09 | — | — | EP | disclosed |