Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172054 | 0.82 | AKR1C3 (0.48) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL6973224 | 0.78 | PPARA (0.43) | KMT2ALMNAMAPTALDH1A1CYP1A2 | |
| SCHEMBL5852107 | 0.78 | MAPT (0.65) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL27965888 | 0.76 | ALDH1A1 (0.47) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL6982722 | 0.76 | KEAP1 (0.45) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8809496 | 0.74 | ALDH1A1 (0.46) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL6918330 | 0.73 | MEN1 (0.47) | KMT2AMEN1LMNAALDH1A1CTSD | |
| SCHEMBL7566672 | 0.73 | GAA (0.47) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL9701512 | 0.73 | L3MBTL1 (0.45) | KMT2AMEN1LMNAPOLBCTSD | |
| SCHEMBL7370107 | 0.72 | NR3C2 (0.63) | NR3C2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042656-A1 | NOVEL COMPOUNDS | CYTEL CORPORATION (US) | 1998-10-01 | — | — | WO | disclosed |