Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | ATM | Q13315 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815758 | 0.81 | CA12 (0.46) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL8808484 | 0.76 | KDM4E (0.52) | CA12CA9KMT2AMEN1KDM4E | |
| SCHEMBL14579885 | 0.76 | KDM4E (0.52) | CA12CA9KMT2AMEN1KDM4E | |
| SCHEMBL6490439 | 0.74 | AKR1B1 (0.54) | CA12CA9KMT2AMEN1KDM4E | |
| SCHEMBL8816911 | 0.70 | CA9 (0.50) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL30002655 | 0.69 | POLB (0.57) | CA12CA1CA9KMT2AATM | |
| SCHEMBL14259812 | 0.69 | ALDH2 (0.47) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL2274941 | 0.69 | POLB (0.57) | CA12CA1CA9KMT2AATM | |
| SCHEMBL4150207 | 0.69 | CA12 (0.48) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL15788790 | 0.69 | TP53 (0.43) | CA12CA1CA2CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696157-A | Sulfonated derivatives of 7-aminocoumarin | MOLECULAR PROBES, INC. (US) | 1997-12-09 | — | — | US | disclosed |