Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.57 |
| ▸ | PPARA | Q07869 | 9/20 | 0.57 |
| ▸ | PPARG | P37231 | 8/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685509 | 0.90 | POLB (0.50) | FFAR1PPARAPPARG | |
| SCHEMBL8811925 | 0.89 | FFAR1 (0.56) | FFAR1PPARAPPARG | |
| SCHEMBL8811662 | 0.87 | CHRNB2 (0.52) | FFAR1PPARAPPARG | |
| SCHEMBL8810491 | 0.85 | PPARG (0.51) | FFAR1PPARG | |
| SCHEMBL8813431 | 0.84 | MAPT (0.56) | FFAR1PPARAPPARG | |
| SCHEMBL8810577 | 0.84 | PARP1 (0.51) | — | |
| SCHEMBL8812051 | 0.83 | HTT (0.52) | FFAR1PPARAPPARG | |
| SCHEMBL8811153 | 0.81 | PPARG (0.53) | FFAR1PPARAPPARG | |
| SCHEMBL8809696 | 0.81 | PPARG (0.41) | PPARAPPARGPPARD | |
| SCHEMBL8811288 | 0.81 | CA2 (0.51) | FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1167111-A | Thiazolidinedione derivatives, method for preparing derivatives and pharmaceutical compositions containing same | SENGA PHARMACEUTICAL LAB INC (JP) | 1997-12-10 | — | — | CN | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |