Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53BP1 | Q12888 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25734619 | 0.81 | ALDH1A1 (0.41) | POLBTP53BP1ALDH1A1MEN1LMNA | |
| SCHEMBL30582766 | 0.81 | POLB (0.38) | POLBTP53BP1ALDH1A1MEN1LMNA | |
| SCHEMBL3314749 | 0.81 | POLB (0.38) | POLBTP53BP1ALDH1A1MEN1LMNA | |
| SCHEMBL4806320 | 0.81 | LMNA (0.46) | POLBALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL18531112 | 0.79 | TP53BP1 (0.38) | POLBTP53BP1ALDH1A1MEN1LMNA | |
| SCHEMBL12091393 | 0.79 | POLB (0.37) | POLBTP53BP1ALDH1A1MEN1LMNA | |
| SCHEMBL22851616 | 0.77 | LMNA (0.41) | POLBTP53BP1ALDH1A1MEN1LMNA | |
| SCHEMBL22039380 | 0.77 | HDAC1 (0.52) | TP53BP1KDM4E | |
| SCHEMBL17574414 | 0.77 | TSHR (0.58) | POLBALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL22851382 | 0.76 | ALDH1A1 (0.50) | POLBTP53BP1ALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765314-A1 | BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-02 | — | — | EP | disclosed |