Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16491136 | 0.91 | ADRA1A (0.55) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL13610844 | 0.91 | ADRA1A (0.55) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL1983625 | 0.85 | LMNA (0.40) | LMNASLC22A6TSHRADRA1APOLB | |
| Hydrochloric Acid SCHEMBL2653260 | 0.83 | NAALAD2 (0.39) | LMNASLC22A6TSHRADRA1APOLB | |
| SCHEMBL16491130 | 0.82 | EPHX2 (0.54) | LMNATSHRADRA1APRMT1HDAC11 | |
| SCHEMBL9979452 | 0.82 | LMNA (0.42) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL25734619 | 0.81 | ALDH1A1 (0.41) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL3314749 | 0.81 | POLB (0.38) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL8809802 | 0.81 | POLB (0.38) | LMNAPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL852157 | 0.80 | TSHR (0.43) | LMNASLC22A6TSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12594700-B2 | Coatings from polyisocyanurate coatings (rim) and their use in injection molding processes | COVESTRO DEUTSCHLAND AG (DE) | 2026-04-07 | — | — | US | disclosed |
| EP-3601405-B1 | GENERATION OF POLYISOCYANURATE LAYERS THROUGH SEPARATE APPLICATION OF ISOCYANATE COMPONENTS AND CATALYSTS | COVESTRO DEUTSCHLAND AG (DE) | 2024-08-28 | — | — | EP | disclosed |
| US-12043637-B2 | Fluorescent dyes containing bis-boron fused heterocycles and uses in sequencing | ILLUMINA CAMBRIDGE LIMITED (GB) | 2024-07-23 | — | — | US | disclosed |
| US-20240067640-A1 | PHENYL MALEIMIDE LINKER AGENTS | FIREFLY BIO, INC. | 2024-02-29 | — | — | US | disclosed |
| US-20230226207-A1 | Camptothecin Drug Having High-Stability Hydrophilic Connecting Unit And Conjugate Thereof | SYSTIMMUNE, INC. | 2023-07-20 | — | — | US | disclosed |
| US-20230211530-A1 | COATINGS FROM POLYISOCYANURATE COATINGS (RIM) AND THEIR USE IN INJECTION MOLDING PROCESSES | COVESTRO DEUTSCHLAND AG (DE) | 2023-07-06 | — | — | US | disclosed |
| EP-4175820-A1 | COATINGS FROM POLYISOCYANURATE COATINGS (RIM) AND THEIR USE IN INJECTION MOLDING PROCESSES | Covestro Deutschland AG (DE) | 2023-05-10 | — | — | EP | disclosed |
| US-11638762-B2 | Targeted delivery of nicotinamide adenine dinucleotide salvage pathway inhibitors | SEAGEN INC. (US) | 2023-05-02 | — | — | US | disclosed |
| US-20220162156-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME | Cellix Bio Provate Limited (IN) | 2022-05-26 | — | — | US | disclosed |
| WO-2022002787-A1 | COATINGS FROM POLYISOCYANURATE COATINGS (RIM) AND THEIR USE IN INJECTION MOLDING PROCESSES | COVESTRO DEUTSCHLAND AG (DE) | 2022-01-06 | — | — | WO | disclosed |
| US-8791142-B2 | Oxazole pyridine derivatives useful as S1P1 receptor agonists | MERCK SERONO S.A. (CH) | 2014-07-29 | — | — | US | disclosed |
| US-8193214-B2 | Chymase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-05 | — | — | US | disclosed |
| US-20110306636-A1 | OXAZOLE PYRIDINE DERIVATIVES USEFUL AS S1P1 RECEPTOR AGONISTS | MERCK SERONO SA (CH) | 2011-12-15 | — | — | US | disclosed |
| US-20110306636-A1 | OXAZOLE PYRIDINE DERIVATIVES USEFUL AS S1P1 RECEPTOR AGONISTS | MERCK SERONO SA (CH) | 2011-12-15 | — | — | US | disclosed |
| US-20100029637-A1 | Chymase Inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-04 | — | — | US | disclosed |
| US-7371807-B2 | Blocked biuretized isocyanates | BAYER MATERIALSCIENCE LLC (US) | 2008-05-13 | — | — | US | disclosed |
| EP-1650245-B1 | Biuretized polyisocyanates blocked with aralkylamines | BAYER MATERIALSCIENCE LLC (US) | 2007-12-19 | — | — | EP | disclosed |
| US-20060089479-A1 | Blocked biuretized isocyanates | COVESTRO LLC | 2006-04-27 | — | — | US | disclosed |
| EP-1650245-A1 | Biuretized polyisocyanates blocked with aralkylamines | Bayer MaterialScience LLC (US) | 2006-04-26 | — | — | EP | disclosed |
| EP-0765314-A1 | BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029637-A1 | Chymase Inhibitors | CMA1, CPA3, SERPINB1 | LMNA 1979/4885SLC22A6 2609/4885TSHR 3397/4885 |
| US-12043637-B2 | Fluorescent dyes containing bis-boron fused heterocycles and uses in sequencing | BLVRB, BCDIN3D, FOSB | LMNA 386/4885SLC22A6 623/4885TSHR 3478/4885 |
| US-20220162156-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME | SI, SLC10A2, F5 | LMNA 4229/4885SLC22A6 339/4885TSHR 3380/4885 |
| US-20230226207-A1 | Camptothecin Drug Having High-Stability Hydrophilic Connecting Unit And Conjugate Thereof | SLC7A1, CD44, DCLRE1A | LMNA 2482/4885SLC22A6 54/4885TSHR 1385/4885 |
| US-12594700-B2 | Coatings from polyisocyanurate coatings (rim) and their use in injection molding processes | TST, C9, ESD | LMNA 4756/4885SLC22A6 2684/4885TSHR 3835/4885 |
| US-20110306636-A1 | OXAZOLE PYRIDINE DERIVATIVES USEFUL AS S1P1 RECEPTOR AGONISTS | S1PR1, S1PR3, S1PR5 | LMNA 3976/4885SLC22A6 3180/4885TSHR 783/4885 |
| US-20240067640-A1 | PHENYL MALEIMIDE LINKER AGENTS | TPX2, H1-4, MAPT | LMNA 233/4885SLC22A6 344/4885TSHR 1144/4885 |
| US-11638762-B2 | Targeted delivery of nicotinamide adenine dinucleotide salvage pathway inhibitors | NAMPT, NME4, NNMT | LMNA 1619/4885SLC22A6 682/4885TSHR 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.