Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | CES1 | P23141 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249473 | 0.79 | TTR (0.43) | TTRALOX5APFEN1TRPA1GRM5 | |
| SCHEMBL18855031 | 0.78 | AKR1C2 (0.44) | LMNAHSD17B1HSD17B2SLC6A4 | |
| SCHEMBL9565253 | 0.78 | TTR (0.46) | TTRALOX5APFEN1CES2CES1 | |
| SCHEMBL14152886 | 0.77 | TTR (0.47) | TTRALOX5APFEN1PDE3BPDE3A | |
| SCHEMBL2709632 | 0.77 | HPRT1 (0.35) | CES2CES1NPC1LMNAAR | |
| SCHEMBL1710681 | 0.75 | TTR (0.41) | TTRALOX5APFEN1PDE3BPDE3A | |
| SCHEMBL29000156 | 0.75 | ACHE (0.43) | TTRALOX5APFEN1PTGESCSNK1D | |
| SCHEMBL2725203 | 0.75 | CYP1A2 (0.37) | AR | |
| SCHEMBL2710387 | 0.75 | CYP1A2 (0.40) | NPC1RAB9AAR | |
| SCHEMBL14555702 | 0.75 | TRPV4 (0.48) | TTRALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433923-A1 | CHLOROBENZENE DERIVATIVE, OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM, AND OPTICAL ELEMENT | JNC Corporation (JP) | 2012-03-28 | — | — | EP | disclosed |