Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | HTR2A | P28223 | 15/20 | 0.53 |
| ▸ | HTR7 | P34969 | 14/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808853 | 0.91 | DRD2 (0.62) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL8809389 | 0.85 | DRD2 (0.39) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL8808675 | 0.85 | DRD2 (0.61) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL8810867 | 0.81 | DRD2 (0.58) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL8807844 | 0.80 | DRD2 (0.61) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL8808671 | 0.77 | DRD2 (0.60) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL8808524 | 0.77 | DRD2 (0.54) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL1545611 | 0.76 | ACHE (0.93) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL27443771 | 0.76 | DRD2 (0.74) | DRD2SLC6A4ACHEHTR2AHTR7 | |
| SCHEMBL1545164 | 0.74 | DRD2 (0.76) | DRD2SLC6A4ACHEHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794185-A1 | BICYCLIC THIAZOLE COMPOUND | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-10 | — | — | EP | claimed |
| EP-0794185-A1 | BICYCLIC THIAZOLE COMPOUND | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-10 | — | — | EP | disclosed |