Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 10/20 | 0.36 |
| ▸ | HTR7 | P34969 | 8/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809944 | 0.85 | DRD2 (0.57) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL8809987 | 0.85 | DRD2 (0.39) | DRD2SLC6A4CTSSHTR2AHTR7 | |
| SCHEMBL8808427 | 0.77 | CTSS (0.38) | DRD2SLC6A4CTSSHTR2AHTR7 | |
| SCHEMBL8808853 | 0.75 | DRD2 (0.62) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL7699932 | 0.71 | DRD2 (0.55) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL7697170 | 0.71 | DRD2 (0.53) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL6890629 | 0.71 | CTSS (0.43) | DRD2SLC6A4CTSSHTR2AACHE | |
| SCHEMBL8810725 | 0.70 | DRD2 (0.39) | DRD2SLC6A4CTSSHTR2AHTR7 | |
| SCHEMBL6898517 | 0.70 | HTR2A (0.46) | DRD2SLC6A4CTSSHTR2AKCNH2 | |
| SCHEMBL7701569 | 0.70 | HTR2C (0.61) | DRD2SLC6A4HTR2AHTR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794185-A1 | BICYCLIC THIAZOLE COMPOUND | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-10 | — | — | EP | claimed |
| EP-0794185-A1 | BICYCLIC THIAZOLE COMPOUND | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-10 | — | — | EP | disclosed |