Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30170219 | 1.00 | S100B (0.49) | S100BGAANPSR1MAPTCA1 | |
| SCHEMBL28518807 | 0.89 | S100B (0.49) | S100BGAANPSR1MAPTCA2 | |
| SCHEMBL5316261 | 0.83 | S100B (0.50) | S100BGAANPSR1MAPTCA1 | |
| SCHEMBL4062029 | 0.83 | S100B (0.50) | S100BGAANPSR1MAPTCA1 | |
| SCHEMBL14804097 | 0.83 | NOS3 (0.50) | S100BGAANPSR1MAPTCA1 | |
| SCHEMBL28242698 | 0.83 | CYP2C9 (0.55) | MAPTCA1CA2NPC1RAB9A | |
| SCHEMBL1259691 | 0.83 | KMT2A (0.52) | S100BGAANPSR1MAPTNPC1 | |
| SCHEMBL809447 | 0.83 | KMT2A (0.52) | S100BGAANPSR1MAPTNPC1 | |
| SCHEMBL12528504 | 0.83 | KMT2A (0.52) | S100BGAANPSR1MAPTNPC1 | |
| SCHEMBL28524109 | 0.83 | LMNA (0.50) | S100BGAANPSR1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997013750-A1 | AZETIDINONES AND THEIR THERAPEUTIC USE AS CYTOKINE INHIBITORS | CHIROSCIENCE LIMITED (GB) | 1997-04-17 | — | — | WO | disclosed |