Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.58 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809369 | 0.89 | SLC2A1 (0.46) | PARP1ABCC2POLBMAPTCSNK2A2 | |
| SCHEMBL8690307 | 0.89 | PARP1 (0.74) | PARP1ABCC2POLBMAPTSIRT1 | |
| SCHEMBL8810629 | 0.89 | PARP1 (0.74) | PARP1ABCC2POLBMAPTSIRT1 | |
| SCHEMBL8809776 | 0.87 | PARP1 (0.64) | PARP1POLBMAPTSIRT1SIRT5 | |
| SCHEMBL8685538 | 0.86 | PARP1 (0.63) | PARP1POLBMAPTSIRT1SIRT5 | |
| SCHEMBL8812789 | 0.85 | SMN1; SMN2 (0.62) | PARP1POLBMAPTSIRT1SIRT5 | |
| SCHEMBL8809356 | 0.83 | PARP1 (0.79) | PARP1POLBMAPTSIRT1SIRT5 | |
| SCHEMBL8811262 | 0.83 | PARP1 (0.58) | PARP1POLBSIRT1SIRT5LMNA | |
| SCHEMBL8810078 | 0.82 | CSNK2A2 (0.45) | PARP1ABCC2CSNK2A2CLK1CSNK2B | |
| SCHEMBL8810237 | 0.81 | PARP1 (0.61) | PARP1POLBMAPTSIRT1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |