SCHEMBL8809665

SCHEMBL8809665

CC(C)C[C@H](CN[C@H]1CCOC1O)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 5/20 0.42
PIN1 Q13526 1/20 0.41
CASP3 P42574 2/20 0.41
KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8807949 0.87 CAPN1 (0.42) CAPN1PIN1CASP3KMT2A
SCHEMBL4560987 0.84 CAPN1 (0.58) CAPN1
SCHEMBL8810857 0.83 CAPN1 (0.49) CAPN1CASP3
SCHEMBL8404287 0.82 CAPN1 (0.51) CAPN1CASP3
SCHEMBL8407723 0.81 CYP1A2 (0.43) CAPN1CASP3KMT2A
SCHEMBL8810652 0.80 CAPN1 (0.48) CAPN1
SCHEMBL8810844 0.79 SMN1; SMN2 (0.39) CAPN1
SCHEMBL8807979 0.79 CTSK (0.43) CAPN1
SCHEMBL8810894 0.79 CAPN1 (0.41) CAPN1
SCHEMBL29398691 0.78 CASP3 (0.50) CASP3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0810221-A1 OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES MITSUBISHI CHEMICAL CORPORATION (JP) 1997-12-03 EP disclosed