Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812096 | 0.93 | ALDH1A1 (0.40) | KMT2AALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL8809135 | 0.82 | MAP4K4 (0.45) | NMT1KMT2AALDH1A1MEN1 | |
| SCHEMBL8810145 | 0.80 | KMT2A (0.57) | BCHEFYNNMT1METAP2MPO | |
| SCHEMBL5800759 | 0.79 | KMT2A (0.52) | KMT2AALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL27623829 | 0.77 | MAOB (0.40) | FYNKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8810656 | 0.76 | TRIM24 (0.38) | KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL28044043 | 0.74 | MAOB (0.43) | FYNALDH1A1KDM4ESMN1; SMN2TDP1 | |
| SCHEMBL3847454 | 0.71 | MAOB (0.40) | KMT2AALDH1A1KDM4E | |
| SCHEMBL9234564 | 0.71 | KMT2A (0.38) | FYNKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9404829 | 0.70 | DYRK1A (0.42) | TACR1FYNKMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |