Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 2/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810782 | 0.82 | BCHE (0.37) | ALDH1A1NMT1MEN1KMT2A | |
| SCHEMBL8809947 | 0.81 | MAP4K4 (0.50) | MAP4K4CARM1PRMT6POLBKCNH2 | |
| SCHEMBL8812096 | 0.76 | ALDH1A1 (0.40) | POLBALDH1A1MEN1KMT2A | |
| SCHEMBL8807848 | 0.76 | HRH3 (0.62) | MAP4K4CARM1PRMT6POLBKCNH2 | |
| SCHEMBL8812898 | 0.76 | MAP4K4 (0.42) | MAP4K4CARM1PRMT6POLBKCNH2 | |
| SCHEMBL18984688 | 0.72 | MAP4K4 (0.56) | MAP4K4CARM1PRMT6POLBKCNH2 | |
| SCHEMBL5800759 | 0.71 | KMT2A (0.52) | ALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL8808906 | 0.70 | HRH3 (0.55) | POLBALDH1A1PARP1HRH3CXCR4 | |
| SCHEMBL8809463 | 0.70 | ALDH1A1 (0.51) | MAP4K4POLBKCNH2ALDH1A1PARP1 | |
| SCHEMBL8809605 | 0.70 | ALDH1A1 (0.51) | MAP4K4POLBKCNH2ALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |