Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810782 | 0.93 | BCHE (0.37) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27623829 | 0.79 | MAOB (0.40) | ALDH1A1LMNAMAPTMAPK1TP53 | |
| SCHEMBL8809135 | 0.76 | MAP4K4 (0.45) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9059722 | 0.76 | PTGES (0.38) | ALDH1A1NPSR1SMN1; SMN2KDM4E | |
| SCHEMBL15164064 | 0.75 | KDM4E (0.50) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8810145 | 0.74 | KMT2A (0.57) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL5800759 | 0.73 | KMT2A (0.52) | ALDH1A1MAPTMAPK1TP53SMN1; SMN2 | |
| SCHEMBL3847454 | 0.72 | MAOB (0.40) | ALDH1A1MAPK1KMT2AKDM4E | |
| SCHEMBL8810656 | 0.71 | TRIM24 (0.38) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL8808848 | 0.69 | SMN1; SMN2 (0.46) | ALDH1A1LMNAMAPTMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |