Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 2/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.55 |
| ▸ | UBE2M | P61081 | 1/20 | 0.48 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855625 | 0.92 | SOAT2 (0.52) | SOAT2SOAT1UBE2MDCUN1D1LMNA | |
| SCHEMBL854382 | 0.91 | SOAT1 (0.47) | SOAT2SOAT1UBE2MDCUN1D1LMNA | |
| SCHEMBL10189418 | 0.90 | SOAT2 (0.48) | SOAT2SOAT1UBE2MDCUN1D1LMNA | |
| SCHEMBL853667 | 0.89 | UBE2M (0.49) | SOAT2SOAT1UBE2MDCUN1D1LMNA | |
| SCHEMBL855984 | 0.87 | SOAT2 (0.47) | SOAT2SOAT1UBE2MDCUN1D1LMNA | |
| SCHEMBL855668 | 0.85 | UBE2M (0.48) | SOAT2SOAT1UBE2MDCUN1D1 | |
| SCHEMBL856560 | 0.85 | SMN1; SMN2 (0.46) | SOAT2SOAT1UBE2MDCUN1D1LMNA | |
| SCHEMBL855709 | 0.85 | SOAT2 (0.50) | SOAT2SOAT1UBE2MDCUN1D1LMNA | |
| SCHEMBL855314 | 0.84 | LMNA (0.43) | SOAT2SOAT1UBE2MDCUN1D1LMNA | |
| SCHEMBL856449 | 0.83 | UBE2M (0.47) | UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1308438-B9 | 3-SUBSTITUTED UREA DERIVATIVES AND MEDICINAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-28 | — | — | EP | disclosed |
| EP-1308438-B1 | 3-SUBSTITUTED UREA DERIVATIVES AND MEDICINAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2010-10-20 | — | — | EP | disclosed |