Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 18/20 | 0.52 |
| ▸ | GRPR | P30550 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856322 | 0.85 | NMBR (0.47) | NMBRGRPR | |
| SCHEMBL9680304 | 0.74 | MAPT (0.58) | NMBRGRPRKDM4EAPAF1POLB | |
| SCHEMBL13328416 | 0.72 | MEN1 (0.65) | NMBRMAPT | |
| SCHEMBL856560 | 0.72 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL855625 | 0.71 | SOAT2 (0.52) | — | |
| SCHEMBL6181687 | 0.71 | NMBR (0.80) | NMBRGRPRMAPT | |
| SCHEMBL881081 | 0.70 | SOAT2 (0.55) | — | |
| SCHEMBL10189418 | 0.70 | SOAT2 (0.48) | — | |
| SCHEMBL855709 | 0.69 | SOAT2 (0.50) | — | |
| SCHEMBL855694 | 0.69 | S1PR4 (0.43) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1308438-B9 | 3-SUBSTITUTED UREA DERIVATIVES AND MEDICINAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-28 | — | — | EP | disclosed |