Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | NMBR | P28336 | 5/20 | 0.58 |
| ▸ | GRPR | P30550 | 1/20 | 0.54 |
| ▸ | RUVBL1 | Q9Y265 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15142948 | 0.86 | KDM4E (0.64) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL15142954 | 0.86 | KDM4E (0.64) | MAPTKDM4EMEN1LMNAMPO | |
| Hydrochloric Acid SCHEMBL19747609 | 0.81 | KMT2A (0.67) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL9610738 | 0.81 | MEN1 (0.71) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL7648711 | 0.81 | KDM4E (0.67) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL9609465 | 0.81 | MEN1 (0.71) | MAPTKDM4EMEN1LMNAMPO | |
| Hydrochloric Acid SCHEMBL19748758 | 0.81 | RUVBL1 (0.73) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL30767397 | 0.81 | MEN1 (0.71) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL631048 | 0.80 | KDM4E (0.70) | MAPTKDM4EMEN1LMNAMPO | |
| SCHEMBL876693 | 0.80 | KDM4E (0.70) | MAPTKDM4EMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |