Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808959 | 0.93 | PTGIR (0.47) | PTGIRSIGMAR1 | |
| SCHEMBL8414338 | 0.87 | ACHE (0.46) | ACHEMTNR1AMTNR1BMAOAMAOB | |
| SCHEMBL8811042 | 0.87 | MTNR1A (0.42) | ACHEMTNR1AMTNR1BPTGIRSIGMAR1 | |
| SCHEMBL9050358 | 0.86 | PTGIR (0.43) | ACHEMAOAMAOBPTGIR | |
| SCHEMBL8808628 | 0.86 | PTGIR (0.50) | PTGIRSIGMAR1 | |
| SCHEMBL9050353 | 0.84 | ACHE (0.43) | ACHEMAOAMAOBPTGIRBCHE | |
| SCHEMBL8809395 | 0.83 | PTGIR (0.48) | PTGIRSIGMAR1 | |
| SCHEMBL8808958 | 0.81 | PTGIR (0.46) | PTGIRSIGMAR1 | |
| SCHEMBL8411211 | 0.81 | PTGIR (0.47) | PTGIRSIGMAR1 | |
| SCHEMBL8811210 | 0.80 | PTGIR (0.44) | PTGIRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5589496-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor agonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |