Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20178540 | 0.81 | IDO1 (0.45) | RAB9AL3MBTL1SMN1; SMN2NPC1ACLY | |
| SCHEMBL23850221 | 0.80 | RAB9A (0.42) | RAB9AL3MBTL1SMN1; SMN2NPC1ACLY | |
| SCHEMBL8212790 | 0.79 | ACLY (0.53) | RAB9AL3MBTL1SMN1; SMN2NPC1ACLY | |
| SCHEMBL4842993 | 0.77 | MEN1 (0.44) | SMN1; SMN2LMNAALDH1A1HTTTDP1 | |
| SCHEMBL8811824 | 0.77 | ALDH1A1 (0.48) | NMT1ALDH1A1CARM1 | |
| SCHEMBL14589083 | 0.77 | RAB9A (0.59) | RAB9AL3MBTL1SMN1; SMN2NPC1AOC3 | |
| SCHEMBL13949684 | 0.77 | RAB9A (0.68) | RAB9AL3MBTL1SMN1; SMN2NPC1AOC3 | |
| SCHEMBL344042 | 0.77 | RAB9A (0.53) | RAB9AL3MBTL1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL5696903 | 0.76 | RAB9A (0.67) | RAB9AL3MBTL1SMN1; SMN2NPC1AOC3 | |
| SCHEMBL8810145 | 0.74 | KMT2A (0.57) | SMN1; SMN2LMNANMT1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |