SCHEMBL881174

SCHEMBL881174

OOOOOOCC1CCCC1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PARP15 Q460N3 3/20 0.33
PARP10 Q53GL7 3/20 0.33
LMNA P02545 1/20 0.33
SLC1A3 P43003 3/20 0.32
SLC1A2 P43004 3/20 0.32
SLC1A1 P43005 3/20 0.32
PARP2 Q9UGN5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14064309 1.00 PARP15 (0.33) PARP15PARP10LMNASLC1A3SLC1A2
SCHEMBL14175954 0.91
SCHEMBL13082529 0.88 LMNA (0.38) PARP15PARP10LMNASLC1A3SLC1A2
SCHEMBL12693768 0.86
SCHEMBL14189181 0.80
SCHEMBL6805536 0.76 NFE2L2 (0.34)
SCHEMBL13523824 0.74 NFE2L2 (0.30)
SCHEMBL11682621 0.72 CTSL (0.41) PARP15PARP10LMNASLC1A3SLC1A2
SCHEMBL21614191 0.71 CTSL (0.31) LMNA
SCHEMBL12417003 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120117237-A1 SYSTEM AND METHOD EMPLOYING AN AGILE NETWORK PROTOCOL FOR SECURE COMMUNICATIONS USING SECURE DOMAIN NAMES VIRNETX, INC. (US) 2012-05-10 US disclosed
US-20120117382-A1 SYSTEM AND METHOD EMPLOYING AN AGILE NETWORK PROTOCOL FOR SECURE COMMUNICATIONS USING SECURE DOMAIN NAMES VIRNETX, INC. (US) 2012-05-10 US disclosed
US-20120110103-A1 SYSTEM AND METHOD EMPLOYING AN AGILE NETWORK PROTOCOL FOR SECURE COMMUNICATIONS USING SECURE DOMAIN NAMES VIRNETX, INC. (US) 2012-05-03 US disclosed
US-20120102204-A1 SYSTEM AND METHOD EMPLOYING AN AGILE NETWORK PROTOCOL FOR SECURE COMMUNICATIONS USING SECURE DOMAIN NAMES VIRNETX, INC. (US) 2012-04-26 US disclosed
US-20120102206-A1 SYSTEM AND METHOD EMPLOYING AN AGILE NETWORK PROTOCOL FOR SECURE COMMUNICATIONS USING SECURE DOMAIN NAMES VIRNETX, INC. (US) 2012-04-26 US disclosed
US-20120096541-A1 SYSTEM AND METHOD EMPLOYING AN AGILE NETWORK PROTOCOL FOR SECURE COMMUNICATIONS USING SECURE DOMAIN NAMES VIRNETX, INC. (US) 2012-04-19 US disclosed
US-20120078376-A1 Method And Apparatus For Wrist Arthroplasty BIOMET MANUFACTURING CORP. (US) 2012-03-29 US disclosed