Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379127 | 0.93 | GAA (0.44) | GAASGMS2RECQLMEN1KMT2A | |
| SCHEMBL7376600 | 0.92 | RXRA (0.48) | GAASGMS2RECQLMEN1KMT2A | |
| SCHEMBL7372095 | 0.90 | GAA (0.42) | GAASGMS2RECQLMEN1KMT2A | |
| SCHEMBL7368652 | 0.88 | RECQL (0.48) | GAARECQLMEN1KMT2AMAPT | |
| SCHEMBL7369621 | 0.87 | SGMS2 (0.55) | GAASGMS2MEN1KMT2ANPC1 | |
| SCHEMBL7372435 | 0.87 | RECQL (0.46) | GAARECQLMEN1KMT2AMAPT | |
| SCHEMBL7378156 | 0.86 | LRRK2 (0.48) | GAASGMS2MEN1KMT2AMAPT | |
| SCHEMBL7375995 | 0.86 | CYP19A1 (0.51) | GAASGMS2RECQLMEN1KMT2A | |
| SCHEMBL7373554 | 0.86 | RECQL (0.46) | GAARECQLMEN1KMT2AMAPT | |
| SCHEMBL7374059 | 0.86 | EGFR (0.46) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |