Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749370 | 0.93 | CYP19A1 (0.49) | CYP19A1GAASGMS2LRRK2 | |
| SCHEMBL7378156 | 0.93 | LRRK2 (0.48) | CYP19A1GAASGMS2LRRK2L3MBTL1 | |
| SCHEMBL7374553 | 0.92 | MEN1 (0.48) | CYP19A1MAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7554720 | 0.90 | MEN1 (0.49) | GAAL3MBTL1MAPTSMN1; SMN2RECQL | |
| SCHEMBL7376600 | 0.89 | RXRA (0.48) | CYP19A1GAASGMS2MAPTSMN1; SMN2 | |
| SCHEMBL7379998 | 0.88 | L3MBTL1 (0.41) | CYP19A1GAAL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL7379127 | 0.88 | GAA (0.44) | CYP19A1GAASGMS2MAPTSMN1; SMN2 | |
| SCHEMBL7378099 | 0.87 | L3MBTL1 (0.43) | GAAL3MBTL1MAPTSMN1; SMN2RECQL | |
| SCHEMBL7369621 | 0.87 | SGMS2 (0.55) | CYP19A1GAASGMS2LRRK2NPC1 | |
| SCHEMBL8812409 | 0.86 | GAA (0.43) | CYP19A1GAASGMS2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |