Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317723 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL2847064 | 0.74 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2PDE3B | |
| SCHEMBL2847067 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL9300789 | 0.72 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL8424993 | 0.68 | KDM4E (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL31195781 | 0.68 | KDM4E (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL7983948 | 0.68 | KDM4E (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL14644670 | 0.67 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL31664560 | 0.67 | KDM4E (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D | |
| SCHEMBL7983954 | 0.67 | ALDH1A1 (0.70) | KDM4EALDH1A1HPGDSMN1; SMN2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679773-A | SOLID PHASE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V (GB) | 1997-10-21 | — | — | US | disclosed |