Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 8/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812607 | 0.90 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1NPSR1POLBRXFP1 | |
| SCHEMBL20403452 | 0.83 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1NPSR1POLBRXFP1 | |
| SCHEMBL8809643 | 0.83 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1NPSR1POLBRXFP1 | |
| SCHEMBL17657864 | 0.80 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1NPSR1POLBRXFP1 | |
| SCHEMBL8808546 | 0.80 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1NPSR1POLBRXFP1 | |
| SCHEMBL8811740 | 0.75 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1NPSR1POLBRXFP1 | |
| SCHEMBL16636596 | 0.74 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1NPSR1POLBRXFP1 | |
| SCHEMBL10998811 | 0.72 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1NPSR1POLBRXFP1 | |
| SCHEMBL636234 | 0.71 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1NPSR1POLBRXFP1 | |
| SCHEMBL20403453 | 0.67 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1NPSR1POLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794185-A1 | BICYCLIC THIAZOLE COMPOUND | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-10 | — | — | EP | disclosed |