Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811740 | 0.92 | ALDH1A1 (0.38) | ALDH1A1MAPTPKMKDM4EHSD17B10 | |
| SCHEMBL8810218 | 0.85 | SMN1; SMN2 (0.37) | ALDH1A1MAPTPKMKDM4EHSD17B10 | |
| SCHEMBL8812973 | 0.83 | L3MBTL1 (0.49) | ALDH1A1MAPTPKMNPSR1L3MBTL1 | |
| SCHEMBL8808546 | 0.82 | ALDH1A1 (0.37) | ALDH1A1MAPTPKMNPSR1L3MBTL1 | |
| SCHEMBL8812607 | 0.82 | L3MBTL1 (0.45) | ALDH1A1MAPTPKMKDM4EHSD17B10 | |
| SCHEMBL8809403 | 0.79 | MAPT (0.47) | ALDH1A1MAPTPKMKDM4ETP53 | |
| SCHEMBL24984391 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTPKMKDM4EHSD17B10 | |
| SCHEMBL8811818 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MAPTPKMKDM4EHSD17B10 | |
| SCHEMBL8810325 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MAPTPKMKDM4EHSD17B10 | |
| SCHEMBL8809096 | 0.72 | MAPK9 (0.39) | ALDH1A1MAPTKDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794185-A1 | BICYCLIC THIAZOLE COMPOUND | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-10 | — | — | EP | disclosed |