Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.30 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399520 | 0.84 | HTT (0.36) | HTTPOLBCYP19A1CA1CA2 | |
| SCHEMBL4135825 | 0.79 | ALDH1A1 (0.40) | HTT | |
| SCHEMBL2185238 | 0.78 | TRPA1 (0.41) | UGT2B7MCL1CYP1A2APLNR | |
| SCHEMBL30585225 | 0.74 | PTPN2 (0.46) | UGT2B7CYP19A1 | |
| SCHEMBL30585222 | 0.74 | PTPN2 (0.46) | UGT2B7CYP19A1 | |
| SCHEMBL25396197 | 0.74 | PTPN2 (0.46) | UGT2B7CYP19A1 | |
| SCHEMBL20599606 | 0.74 | SMN1; SMN2 (0.36) | HTTAPLNRPOLB | |
| SCHEMBL4254045 | 0.70 | CA1 (0.39) | POLBCYP19A1CA1CA2CA4 | |
| SCHEMBL25137147 | 0.70 | CA1 (0.39) | POLBCYP19A1CA1CA2CA4 | |
| SCHEMBL29007117 | 0.69 | MCL1 (0.36) | HTTMCL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549073-B1 | Novel 2-saccharinylmethyl and 4,5,6,7-tetrahydro-2-saccharinylmethyl phosphates, phosphonates and phosphinates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | SANOFI SA (FR) | 1997-03-26 | — | — | EP | disclosed |