SCHEMBL11399520

SCHEMBL11399520

CC(=O)C1C(=O)CCCC1(C)C

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.36
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PTPN2 P17706 1/20 0.31
PTPN1 P18031 1/20 0.31
POLB P06746 1/20 0.31
CYP19A1 P11511 2/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8813613 0.84 UGT2B7 (0.33) HTTPOLBCYP19A1CA1CA2
SCHEMBL4135825 0.79 ALDH1A1 (0.40) HTTALDH1A1
SCHEMBL4359741 0.78 TRPA1 (0.41) ALDH1A1TDP1PTPN2PTPN1
SCHEMBL14248383 0.75 ALDH1A1 (0.41) HTTALDH1A1
SCHEMBL25137147 0.70 CA1 (0.39) POLBCYP19A1CA1CA2CA4
SCHEMBL4254045 0.70 CA1 (0.39) POLBCYP19A1CA1CA2CA4
SCHEMBL8380889 0.69 CYP2C19 (0.30)
SCHEMBL9122284 0.69 PTPN1 (0.39) HTTALDH1A1TDP1PTPN1POLB
SCHEMBL17609884 0.68 CA1 (0.33) POLBCYP19A1CA1CA2CA4
SCHEMBL31389834 0.68 CA1 (0.33) POLBCYP19A1CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55105639-A None JP disclosed
JP-S55105639-A PREPARATION OF GAMMA-DAMASCONE TOYOTAMA KORYO KK 1980-08-13 JP disclosed