Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13686673 | 0.83 | PRKCA (0.52) | TSHRCYP3A4TDP1ATMPRKCA | |
| Hydrochloric Acid SCHEMBL29006988 | 0.82 | CA2 (0.40) | TSHRCYP3A4TDP1ATMPRKCA | |
| SCHEMBL20747627 | 0.82 | MAPT (0.42) | PRKCAMMP8 | |
| SCHEMBL14198532 | 0.79 | TSHR (0.38) | TSHRCYP3A4TDP1ATMPRKCA | |
| SCHEMBL26356786 | 0.79 | TSHR (0.38) | TSHRCYP3A4TDP1ATMPRKCA | |
| Hydrochloric Acid SCHEMBL29006949 | 0.79 | TSHR (0.32) | TSHRCYP3A4TDP1ATMCA2 | |
| SCHEMBL21569976 | 0.78 | PRKCA (0.38) | PRKCA | |
| SCHEMBL4678856 | 0.78 | TSHR (0.43) | TSHRTDP1PRKCAALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL18492123 | 0.77 | TSHR (0.42) | TSHRTDP1PRKCAALDH1A1HSD17B10 | |
| SCHEMBL12076262 | 0.75 | PRKCA (0.48) | TSHRCYP3A4TDP1ATMPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332996-B | L-ribofuranose type anti-coronavirus compound, and preparation method and application thereof | 南京颐媛生物医学研究院有限公司 | 2025-04-01 | — | — | CN | claimed |
| CN-116332996-A | Anti-coronavirus compound, preparation method and application thereof | 南京颐媛生物医学研究院有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-116332996-B | L-ribofuranose type anti-coronavirus compound, and preparation method and application thereof | 南京颐媛生物医学研究院有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-116332996-A | Anti-coronavirus compound, preparation method and application thereof | 南京颐媛生物医学研究院有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-10208045-B2 | Aza-pyridone compounds and uses thereof | ALIOS BIOPHARMA, INC. (US) | 2019-02-19 | — | — | US | disclosed |
| WO-2012039787-A1 | 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208045-B2 | Aza-pyridone compounds and uses thereof | PNPO, ITPA, PDXK | TSHR 2479/4885CYP3A4 279/4885TDP1 1026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.