Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8132407 | 0.98 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL30088433 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL23832407 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL13814572 | 0.80 | GABRP (0.42) | SMN1; SMN2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1736045 | 0.78 | MEN1 (0.46) | SMN1; SMN2NPC1RAB9AMAPTMEN1 | |
| SCHEMBL5618326 | 0.77 | ALDH1A1 (0.57) | SMN1; SMN2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL15267699 | 0.74 | KMT2A (0.60) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL1866130 | 0.73 | TSHR (0.46) | SMN1; SMN2NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL29518679 | 0.73 | TSHR (0.46) | SMN1; SMN2NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL23832385 | 0.73 | NPC1 (0.64) | SMN1; SMN2NPC1RAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679778-A | FOR FORMING CONJUGATES WITH MACROMOLECULES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1997-10-21 | — | — | US | disclosed |
| EP-0667859-A1 | MOLECULE LABELLING USING 2-HYDRANINOPYRIDINE DERIVATIVES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1995-08-23 | — | — | EP | disclosed |