Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 12/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815721 | 0.90 | KDM4E (0.53) | KMT2AMEN1ADORA2ATGFBR1MAPK14 | |
| SCHEMBL8818491 | 0.89 | IGF1R (0.43) | KMT2AMEN1ADORA2ATGFBR1MAPK14 | |
| SCHEMBL8816854 | 0.89 | ADORA2A (0.45) | KMT2AMEN1ADORA2ATGFBR1MAPK14 | |
| SCHEMBL8816582 | 0.88 | ADORA2A (0.58) | KMT2AMEN1ADORA2ATGFBR1MAPK14 | |
| SCHEMBL8817891 | 0.85 | TGFBR1 (0.47) | KMT2AADORA2ATGFBR1MAPK14ALDH1A1 | |
| SCHEMBL8818706 | 0.83 | TGFBR1 (0.46) | ADORA2ATGFBR1MAPK14LMNA | |
| SCHEMBL8817338 | 0.83 | TGFBR1 (0.47) | ADORA2ATGFBR1MAPK14LMNACYP1A2 | |
| SCHEMBL8818148 | 0.83 | MEN1 (0.50) | KMT2AMEN1ADORA2ATGFBR1MAPK14 | |
| SCHEMBL8818694 | 0.82 | ADORA2A (0.48) | KMT2AMEN1ADORA2ATGFBR1MAPK14 | |
| SCHEMBL8818335 | 0.82 | L3MBTL1 (0.53) | ABCB1ABCG2ACACAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066122-A1 | 2 - (PYRIDIN- 2 -YL) -QUINAZOLINE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-24 | — | — | WO | disclosed |