Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WHR1 | P49842 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818335 | 0.93 | L3MBTL1 (0.53) | WHR1NPC1RAB9AL3MBTL1ACACA | |
| SCHEMBL8816999 | 0.90 | ABCG2 (0.47) | WHR1TGFBR1MAPK14L3MBTL1ACACA | |
| SCHEMBL8815687 | 0.86 | TGFBR1 (0.49) | TGFBR1MAPK14MEN1NPC1KMT2A | |
| SCHEMBL8816575 | 0.84 | ADORA2A (0.62) | MEN1KMT2ALMNAHPGDABCG2 | |
| SCHEMBL8818254 | 0.84 | ADORA2A (0.58) | TGFBR1MAPK14MEN1KMT2AL3MBTL1 | |
| SCHEMBL8818153 | 0.83 | TGFBR1 (0.46) | TGFBR1MAPK14MEN1NPC1RAB9A | |
| SCHEMBL8816897 | 0.83 | TGFBR1 (0.46) | TGFBR1MAPK14MEN1KMT2AADORA2A | |
| SCHEMBL8819429 | 0.83 | TGFBR1 (0.48) | TGFBR1MAPK14MEN1KMT2AADORA2A | |
| SCHEMBL8815416 | 0.82 | KMT2A (0.47) | TGFBR1MAPK14MEN1KMT2AACACA | |
| SCHEMBL8817507 | 0.82 | TGFBR1 (0.46) | TGFBR1MAPK14MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066122-A1 | 2 - (PYRIDIN- 2 -YL) -QUINAZOLINE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-24 | — | — | WO | disclosed |