Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815721 | 0.91 | KDM4E (0.53) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL8817333 | 0.90 | CRHR1 (0.46) | MEN1KMT2AKDM4EPOLBCRHR1 | |
| SCHEMBL8818637 | 0.88 | GRM2 (0.47) | MAPTLMNAGAAALDH1A1ADORA2A | |
| SCHEMBL8814815 | 0.88 | TGFBR1 (0.43) | MAPTGAAALDH1A1ADORA2ATGFBR1 | |
| SCHEMBL8816582 | 0.87 | ADORA2A (0.58) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL8816502 | 0.85 | MAPT (0.43) | MAPTLMNAGAAALDH1A1ADORA2A | |
| SCHEMBL8815416 | 0.83 | KMT2A (0.47) | MEN1KMT2ALMNATP53TSHR | |
| SCHEMBL8816575 | 0.82 | ADORA2A (0.62) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL8818254 | 0.82 | ADORA2A (0.58) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL8818694 | 0.81 | ADORA2A (0.48) | MEN1KMT2AKDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066122-A1 | 2 - (PYRIDIN- 2 -YL) -QUINAZOLINE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-24 | — | — | WO | disclosed |