Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 2/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814360 | 0.79 | PAM (0.42) | PAMDGKAALDH1A1TSHRLMNA | |
| SCHEMBL8814357 | 0.77 | DGKA (0.43) | PAMDGKAALDH1A1TDP1TSHR | |
| SCHEMBL18009957 | 0.74 | DGKA (0.48) | PAMDGKAALDH1A1TDP1TSHR | |
| SCHEMBL21811919 | 0.73 | DGKA (0.41) | PAMDGKAALDH1A1TDP1TSHR | |
| SCHEMBL24597734 | 0.72 | CYP1A2 (0.59) | GAAPAMDGKAALDH1A1TDP1 | |
| SCHEMBL47126 | 0.72 | CYP1A2 (0.59) | GAAPAMDGKAALDH1A1TDP1 | |
| SCHEMBL1703446 | 0.72 | CYP1A2 (0.59) | GAAPAMDGKAALDH1A1TDP1 | |
| SCHEMBL1005765 | 0.72 | CYP1A2 (0.59) | GAAPAMDGKAALDH1A1TDP1 | |
| SCHEMBL3862786 | 0.72 | CYP1A2 (0.59) | GAAPAMDGKAALDH1A1TDP1 | |
| SCHEMBL318062 | 0.72 | CYP1A2 (0.59) | GAAPAMDGKAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622944-A | MODIFIED 17-HYDROXY STEROL; TRANSDERMAL ELECTROTRANSPORT ENHANCEMENT | AFFYMAX TECHNOLOGIES N.V. (GB) | 1997-04-22 | — | — | US | disclosed |