Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 2/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8359130 | 0.91 | PAM (0.48) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL8359442 | 0.84 | TSHR (0.55) | PAMTSHRMAPTLMNAALDH1A1 | |
| SCHEMBL8814357 | 0.84 | DGKA (0.43) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL18009957 | 0.81 | DGKA (0.48) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL21811919 | 0.81 | DGKA (0.41) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL8813366 | 0.81 | PAM (0.41) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL1693910 | 0.79 | DGKA (0.64) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL31721561 | 0.79 | DGKA (0.64) | PAMDGKATSHRMAPTLMNA | |
| SCHEMBL8815599 | 0.79 | GAA (0.47) | PAMDGKATSHRLMNAALDH1A1 | |
| SCHEMBL11599455 | 0.77 | DGKA (0.56) | PAMDGKATSHRMAPTDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622944-A | MODIFIED 17-HYDROXY STEROL; TRANSDERMAL ELECTROTRANSPORT ENHANCEMENT | AFFYMAX TECHNOLOGIES N.V. (GB) | 1997-04-22 | — | — | US | disclosed |