Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | TACR1 | P25103 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234454 | 0.88 | LMNA (0.62) | SLC6A2SLC6A3KMT2ATDP1NPC1 | |
| SCHEMBL8775653 | 0.85 | LMNA (0.59) | SLC6A2SLC6A3KMT2ATDP1NPC1 | |
| SCHEMBL550351 | 0.85 | NPC1 (0.60) | SLC6A2SLC6A3KMT2ATDP1NPC1 | |
| SCHEMBL7336549 | 0.85 | SMN1; SMN2 (0.61) | SLC6A2SLC6A3KMT2ATDP1NPC1 | |
| SCHEMBL14099869 | 0.84 | SLC6A2 (0.56) | SLC6A2SLC6A3KMT2ATDP1NPC1 | |
| SCHEMBL6951680 | 0.84 | ALDH1A1 (0.58) | SLC6A2SLC6A3KMT2ATDP1NPC1 | |
| SCHEMBL20143947 | 0.84 | BCL2L1 (0.59) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL5412368 | 0.83 | TACR1 (0.48) | SLC6A2SLC6A3KMT2ATDP1NPC1 | |
| SCHEMBL3068668 | 0.83 | LMNA (0.57) | SLC6A2SLC6A3KMT2ATDP1NPC1 | |
| SCHEMBL2295789 | 0.82 | CA12 (0.66) | SLC6A2SLC6A3KMT2ATDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130079305-A1 | 3-SUBSTITUTED VINYLBORONATES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2013-03-28 | — | — | US | disclosed |
| WO-2011151822-A1 | 3-SUBSTITUTED VINYLBORONATES AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2011-12-08 | — | — | WO | disclosed |
| WO-1997010247-A1 | CLAVULANIC ACID DERIVATIVES FOR TREATING ATHEROSCLEROSIS | SMITHKLINE BEECHAM P.L.C. (GB) | 1997-03-20 | — | — | WO | disclosed |
| CN-1046529-A | Carbostyril derivative | OTSUKA PHARMA CO LTD (JP) | 1990-10-31 | — | — | CN | disclosed |
| US-4258050-A | SYNERGISTS FOR PENICILLINS, CEPHALOSPORINS | BEECHAM GROUP LIMITED (GB) | 1981-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079305-A1 | 3-SUBSTITUTED VINYLBORONATES AND USES THEREOF | VHL, ETV6, MVD | SLC6A2 2944/4885SLC6A3 1045/4885KMT2A 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.