Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17029125 | 0.80 | CASP3 (0.66) | HPGDPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL29783149 | 0.76 | KMT2A (0.60) | HPGDALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL2701523 | 0.76 | KMT2A (0.60) | HPGDALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL30761912 | 0.76 | KMT2A (0.59) | HPGDPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL27377659 | 0.76 | KMT2A (0.59) | HPGDPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL5666942 | 0.75 | ALDH1A1 (0.64) | ALDH1A1IDH1HSD17B10SMN1; SMN2 | |
| SCHEMBL2258501 | 0.73 | KMT2A (0.70) | HPGDKMT2AMEN1ALOX15HTT | |
| SCHEMBL10495293 | 0.73 | SMN1; SMN2 (0.67) | HPGDPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL22343845 | 0.73 | KMT2A (0.56) | HPGDPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL8816529 | 0.73 | CASP3 (0.56) | HPGDPOLBALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684823-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1997-07-09 | — | — | EP | disclosed |
| WO-1997005156-A1 | A NEW ACHIRAL LINKER REAGENT FOR THE INCORPORATION OF MULTIPLE AMINO GROUPS INTO OLIGONUCLEOTIDES | BEHRENS CARSTEN (DK) | 1997-02-13 | — | — | WO | disclosed |
| EP-0684823-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-12-06 | — | — | EP | disclosed |