Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | GUSB | P08236 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | MMP8 | P22894 | 2/20 | 0.56 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457030 | 0.83 | DHODH (0.53) | SMN1; SMN2RAB9ANPC1ALDH1A1PARP1 | |
| SCHEMBL8816597 | 0.82 | MGAM (0.50) | MAPTNPBWR1CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL3336091 | 0.81 | RAB9A (0.80) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL9259477 | 0.81 | MAPT (0.54) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL230979 | 0.80 | DHODH (0.53) | RAB9ANPC1CYP1A2CYP2D6PARP1 | |
| SCHEMBL31027957 | 0.80 | DHODH (0.59) | RAB9ANPC1CYP1A2CYP2D6POLB | |
| SCHEMBL30823383 | 0.79 | PARP1 (0.78) | PARP1PKN1PKN2 | |
| SCHEMBL7146754 | 0.79 | DHODH (0.62) | RAB9ANPC1CYP1A2CYP2D6POLB | |
| SCHEMBL1170898 | 0.79 | DHODH (0.54) | SMN1; SMN2RAB9ANPC1CYP1A2CYP2D6 | |
| SCHEMBL2126513 | 0.77 | MAPT (0.74) | MAPTMEN1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033873-A1 | METHODS OF TREATING OR PREVENTING INTERSTITIAL CYSTITIS | ELI LILLY AND COMPANY (US) | 1997-09-18 | — | — | WO | disclosed |
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |