Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974759 | 0.66 | SLC18A2 (0.35) | — | |
| SCHEMBL29713916 | 0.66 | ALDH1A1 (0.41) | — | |
| SCHEMBL13954409 | 0.66 | ALDH1A1 (0.41) | — | |
| SCHEMBL337013 | 0.66 | ALDH1A1 (0.41) | — | |
| SCHEMBL28974701 | 0.65 | SLC18A2 (0.35) | — | |
| SCHEMBL3306996 | 0.65 | MAPT (0.39) | — | |
| SCHEMBL19617775 | 0.64 | MAPT (0.33) | — | |
| SCHEMBL1760819 | 0.64 | MAPT (0.55) | — | |
| SCHEMBL22255064 | 0.62 | ITGB2 (0.35) | — | |
| SCHEMBL10363588 | 0.62 | RAB9A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997019943-A1 | SUBSTITUTED PIPERAZINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1997-06-05 | — | — | WO | disclosed |