Sugi Predict

Sugi Predict / Compounds / SCHEMBL337013

SCHEMBL337013

SCHEMBL337013

CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCN1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ TSHR P16473 1/20 0.41
▸ NR1H2 P55055 1/20 0.40
▸ MAPT P10636 3/20 0.40
▸ HPGD P15428 2/20 0.39
▸ RECQL P46063 2/20 0.39
▸ USP2 O75604 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ GLA P06280 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ MAPK1 P28482 1/20 0.38
▸ ADORA1 P30542 1/20 0.37
▸ CTSL P07711 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ EPHX1 P07099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13954409 1.00 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ATSHRNR1H2
SCHEMBL29713916 1.00 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ATSHRNR1H2
SCHEMBL30289051 0.87 USP2 (0.44) ALDH1A1MEN1KMT2ANR1H2MAPT
SCHEMBL2392691 0.87 USP2 (0.44) ALDH1A1MEN1KMT2ANR1H2MAPT
SCHEMBL1350453 0.84 USP2 (0.41) ALDH1A1MEN1KMT2ANR1H2MAPT
SCHEMBL881661 0.84 USP2 (0.41) ALDH1A1MEN1KMT2ANR1H2MAPT
SCHEMBL24940 0.84 USP2 (0.41) ALDH1A1MEN1KMT2ANR1H2MAPT
Hydrochloric Acid SCHEMBL14814960 0.83 USP2 (0.41) ALDH1A1MEN1KMT2ANR1H2MAPT
Ammonia Solution, Strong SCHEMBL22169168 0.83 USP2 (0.41) ALDH1A1MEN1KMT2ANR1H2MAPT
SCHEMBL3306996 0.82 MAPT (0.39) ALDH1A1TSHRMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3806661-B1 USE OF ANTAGONISTS OF T2R54 FIRMENICH INCORPORATED (US) 2025-07-02 — — EP disclosed
EP-4566459-A2 ANTAGONISTS OF T2R54 AND COMPOSITIONS AND USES THEREOF Firmenich Incorporated (US) 2025-06-11 — — EP disclosed
US-12295396-B2 Antagonists of T2R54 and compositions and uses thereof FIRMENICH INCORPORATED (US) 2025-05-13 — — US disclosed
US-20240216361-A1 ROR-GAMMA MODULATORS ESCALIER BIOSCIENCES B V (US) 2024-07-04 — — US disclosed
US-20240114942-A1 Antagonists of T2R54 and Compositions and Uses Thereof FIRMENICH INCORPORATED (US) 2024-04-11 — — US disclosed
US-11871772-B2 Antagonists of T2R54 and compositions and uses thereof FIRMENICH INCORPORATED (US) 2024-01-16 — — US disclosed
US-11871772-B2 Antagonists of T2R54 and compositions and uses thereof FIRMENICH INCORPORATED (US) 2024-01-16 — — US disclosed
US-11871772-B2 Antagonists of T2R54 and compositions and uses thereof FIRMENICH INCORPORATED (US) 2024-01-16 — — US disclosed
EP-3623369-B1 NOVEL MORPHOLINYL AMINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE HOFFMANN LA ROCHE (CH) 2023-10-25 — — EP disclosed
US-20230277527-A1 ROR-GAMMA MODULATORS ESCALIER BIOSCIENCES B.V. 2023-09-07 — — US disclosed
WO-2001077104-A1 BICYCLIC HETEROCYLCES, MEDICAMENTS CONTAINING SAID COMPOUNDS, THE USE THEREOF AND METHOD FOR PRODUCING THEM BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2001-10-18 — — WO disclosed
EP-1144368-A2 ACETYLENIC ALPHA-AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS American Cyanamid Company (US) 2001-10-17 — — EP disclosed
US-6297380-B1 2-AMINO-N-(1(R)-BENZYLOXYMETHYL-2-(1,3-DIOXO-8A(S)-PYRIDIN-2 -YLMETHYL-2-(2,2, 2-TRIFLUORO-ETHYL)-HEXAHYDRO-IMIDAZO(1, 5-A)PYRAZIN-7-YL)-2-OXO-ETHYL)-2-METHYL-PROPIONAMIDE IS PREPARED. PFIZER INC. 2001-10-02 — — US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 — — EP disclosed
WO-2001030781-A2 INHIBITORS OF αLβ2 MEDIATED CELL ADHESION TANABE SEIYAKU CO., LTD. (JP) 2001-05-03 — — WO disclosed
US-6225311-B1 Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors AMERICAN CYANAMID COMPANY 2001-05-01 — — US disclosed
CN-1278793-A Sulfonyl derivatives DAIICHI SEIYAKU CO (JP) 2001-01-03 — — CN disclosed
EP-1031563-A1 SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2000-08-30 — — EP disclosed
WO-2000044709-A2 ACETYLENIC α-AMINO ACID-BASED SULFONAMIDE HYDROXAMIC ACID TACE INHIBITORS AMERICAN CYANAMID COMPANY (US) 2000-08-03 — — WO disclosed
EP-1004583-A2 Process and hydantoin intermediates for the synthesis of growth hormone secretagogues Pfizer Products Inc. (US) 2000-05-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11871772-B2 Antagonists of T2R54 and compositions and uses thereof TAS2R50, TAS2R30, TAS2R60 ALDH1A1 3663/4885MEN1 4033/4885KMT2A 2912/4885
US-20230277527-A1 ROR-GAMMA MODULATORS RORB, RORC, RORA ALDH1A1 167/4885MEN1 4775/4885KMT2A 2043/4885
US-20240216361-A1 ROR-GAMMA MODULATORS RORB, RORC, RORA ALDH1A1 167/4885MEN1 4775/4885KMT2A 2043/4885
US-12295396-B2 Antagonists of T2R54 and compositions and uses thereof TAS2R50, TAS2R30, TAS2R60 ALDH1A1 3663/4885MEN1 4033/4885KMT2A 2912/4885
US-20240114942-A1 Antagonists of T2R54 and Compositions and Uses Thereof TAS2R50, TAS2R30, TAS2R60 ALDH1A1 3663/4885MEN1 4033/4885KMT2A 2912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.